Hundreds of millions of people infected! How to prevent Helicobacter pylori?

12-08-2024

Helicobacter pylori (Hp) is a spiral-shaped, slightly anaerobic, very demanding bacteria for growth conditions, has a strong acid resistance, can survive in the stomach for a long time and continue to reproduce, is currently the only found to be parasitic in the stomach microorganism. Helicobacter pylori infection is one of the risk factors leading to gastrointestinal ulcer and gastric cancer, mainly through oral, gastro-oral, fecal-oral transmission. After Helicobacter pylori infection, the main manifestations are pain in the upper abdomen, flatulence, acid reflux, belching, and bad breath.


At present, the global infection rate of Helicobacter pylori is about 50%, and in some developing countries, the infection rate is higher, which can reach more than 80%. Studies have shown that the occurrence of enteric gastric cancer is the result of Helicobacter pylori infection, environmental factors and genetic factors. It is estimated that about 90% of the occurrence of non-cardia gastric cancer is associated with Helicobacter pylori infection, and Helicobacter pylori is considered to be the "culprit" of accelerating or catalyzing the progression of gastric cancer. Therefore, the screening of Helicobacter pylori infection and the eradication of Helicobacter pylori are of great significance in alleviating the symptoms of gastritis, preventing the recurrence of peptic ulcer and reducing the occurrence of gastric cancer.

hpylori test

Helicobacter pylori is listed as a Class I carcinogen by the World Health Organization, but this does not mean that infection with Helicobacter pylori will necessarily develop stomach cancer. However, Helicobacter pylori infection is 1-5 times more likely than non-infected people to develop stomach cancer during their lifetime, and the specific time of developing stomach cancer after infection with Helicobacter pylori cannot be determined. This process varies from person to person, different stages of gastric mucosal lesions, may not have specific clinical symptoms, early gastric cancer may not have any discomfort, only after examination, to know whether they are infected.


At present, the detection methods of Helicobacter pylori are mainly divided into invasive and non-invasive. The most commonly used non-invasive method is urea breath test, that is, carbon 13, carbon 14 breath test, which is internationally recognized as the "gold standard" for Helicobacter pylori examination, this way is simple, rapid, accurate, non-invasive, high sensitivity and specificity, diagnostic accuracy of more than 95%, but carbon 14 breath test is radioactive, not suitable for pregnant women, children. Both carbon 13 and carbon 14 breath tests require fasting and fasting. Non-invasive tests also have antibody assay, antigen assay, by checking whether there are antibodies in the blood and urine, whether there are antigens in the stool to determine, this detection method is inexpensive, easy to operate, no pain, the sensitivity and specificity of the detection is high, 10-15 minutes to obtain the test results, suitable for all populations, suitable for mass screening. Invasive examination refers to the gastroscopy biopsy, the process of gastroscopy may irritate the throat, produce symptoms of retching or nausea, if the reaction symptoms are obvious, it will affect the doctor's examination, the use of gastroscopy for more detailed screening, but also test the patient's patience.

h pylori ab test

Wizbiotech independently developed the gastric helicobacter pylori antigen detection kit (latex method) and Gastric helicobacter pylori antibody detection kit (Colloidal gold method), which has been CE certified and has been praised and recognized by many customers!

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