How does Helicobacter pylori cause stomach cancer step by step?
Helicobacter pylori (Hp) infection has been a significant health problem worldwide, with infection rates as high as 50% globally.
In patients with early gastric cancer, the infection rate of HP is higher, and the risk of gastric cancer in people infected with HP is 4 times that of people not infected with HP.
The mechanism of gastric cancer induced by HP infection is very complex and not completely clear, but the basic principle is related to repeated inflammation of gastric mucosa caused by HP infection. Possible outcomes of Helicobacter pylori infection are as follows: Helicobacter pylori infection → superficial gastritis → atrophic gastritis → intestinal metaplasia → dysplasia → gastric cancer. Therefore, according to the current consensus, when HP infection is detected, we need to do away with it thoroughly.
The clinical symptoms of gastric cancer are complex and varied. Some patients with early gastric cancer have no obvious symptoms, or only show symptoms of chronic gastritis, such as dyspepsia, nausea, vomiting, loss of appetite, etc. The symptoms vary according to different sites, such as vomiting, hematemesis and black stool in distal gastric cancer; Proximal gastric cancer can be manifested as dysphagia, emaciation, etc. In advanced gastric cancer, there may be obvious extreme weakness and cachexia. Therefore, early screening and timely treatment should be done in the early stage of Helicobacter pylori infection.
wizbiotech's Helicobacter pylori Antigen test kit (latex method) for stool sample testing does not require fasting or any special preparation and can be applied at any time according to the patient's situation; It is more economical and no need the machine to read the result, and supports as a common detection reagent for daily health management, helping patients to timely understand the status quo of Helicobacter pylori infection and helping doctors to provide timely treatment plans.
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