What are some specific gastrointestinal conditions that can be diagnosed and managed using fecal calprotectin testing?

03-01-2024

Calprotectin is a protein released by activated neutrophils, which are immune cells involved in the body's response to inflammation. It serves as a valuable biomarker for assessing the severity of intestinal inflammation and monitoring the effectiveness of treatments. Detecting elevated fecal calprotectin levels aids in early diagnosis, guiding treatment decisions, and predicting disease activity in individuals with gastrointestinal disorders.

Some specific conditions that can be assessed using this testing method include:

1、Inflammatory bowel disease (IBD): Fecal calprotectin levels are elevated in patients with Crohn's disease and ulcerative colitis, two forms of IBD. Monitoring calprotectin levels helps assess disease activity, guide treatment decisions, and monitor response to therapy.

2、Irritable bowel syndrome (IBS): Fecal calprotectin testing can help differentiate IBS from IBD, as calprotectin levels are typically normal in IBS patients. This assists in avoiding unnecessary invasive procedures and guiding appropriate management strategies.

3、Gastrointestinal infections: In cases of suspected gastrointestinal infections, measuring fecal calprotectin levels can aid in differentiating between inflammatory and infectious causes. Elevated levels suggest an underlying inflammatory condition.

4、Diverticular disease: Fecal calprotectin testing can help assess the presence of inflammation in patients with diverticulitis, a condition characterized by inflamed pouches in the colon. Elevated calprotectin levels may indicate active inflammation and guide treatment decisions.

5、Celiac disease: Fecal calprotectin testing can be used to assess the presence of ongoing inflammation in patients with celiac disease, an autoimmune disorder triggered by gluten ingestion. Elevated levels may indicate associated inflammation within the gastrointestinal tract.


The fecal calprotectin detection project independently developed and produced by Xiamen Wiz Biotech Co., Ltd is highly sensitive and specific.Its ability to accurately measure fecal calprotectin levels facilitates early diagnosis and monitoring of various intestinal inflammatory diseases. By utilizing this diagnostic tool, healthcare systems can enhance patient care, improve outcomes, and contribute to effective disease management.


Xiamen Wiz Biotech Co., Ltd is a high-tech company engaged in the research and development, production and sales of rapid diagnostic reagents and instruments. Focusing on technological innovation, WIZBIOTECH develops POCT testing reagents and instruments, and takes advantage of existing channels to expand the medical market, with a view to becoming a leader in the field of rapid diagnostic POCT. 

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