G-17,a key marker for gastric cancer screening
Gastrin is a gastrointestinal hormone secreted by the G cells of the antrum and duodenum, which plays an important role in regulating the function of the digestive tract and maintaining its structural integrity. In humans, more than 95% of the bioactive gastrin is alpha-aminated gastrin, mainly consisting of two isomers, G-17 and G-34, of which 80%-90% is G-17. G-17 is only secreted by G cells in the gastric antrum, so it is an important indicator of gastric mucosal injury.
The detection of human serum gastric function with gastrin 17 as the core index is a non-invasive, painless, safe and economical method. This detection project can effectively reduce the risk of gastric cancer, greatly improve the possibility of early diagnosis and treatment of gastric cancer, and is of great significance for the prevention and treatment of various gastric diseases. When the level of gastrin 17 in the body is low, it usually means that the patient has a high acid condition in the stomach. When the level of gastrin 17 is high, it may indicate that there is inflammation in the stomach of the patient, and the patient may have symptoms of hypergastrinemia. This condition can be related to helicobacter pylori infection, stomach ulcers, and the effects of medications.
However, gastrin 17 can only be used as an auxiliary diagnostic test, and the disease cannot be confirmed by relying on gastrin 17 alone. It is necessary to make a comprehensive judgment by combining the value of pepsinogen and PGR, as well as other clinical symptoms and examination results. The combination of gastrin 17, pepsinogen and PGR values can provide a more accurate assessment of gastric function and the basis for disease diagnosis, which is helpful to guide the formulation of treatment and disease monitoring.
Wizbiotech has developed its own pepsinogen I/ Pepsinogen II/ gastrin 17 assay kit (fluorescence immunochromatography), which has been recognized and trusted by many customers. If you need more information and purchase our products, please contact our sales.
